Substance abuse among girls and women is a taboo in many societies especially in Africa. It carries with it many demeaning tags such as…. an incompetent mother, a bad woman, a valueless woman, a sinful woman etc. Punitive drug policies add another tag to women who use drugs i.e. a criminal. These societal tags are stigmatising and lead to discrimination in all spheres of a girls or woman’s life. For example health care workers will say ….I can’t offer treatment to a woman who takes drugs, the law enforcer will say….you are a criminal…..a church pastor will say you are a sinner….community administrator will say…those are drug using women, they have nothing good to offer…These are violation of human rights that significantly affect the quality of life of women who use drugs.  At Women Nest our interventions are contextually relevant and we place community engagement at the heart of everything we do. We advocate for health and human rights of women who use drugs, we fight stigma and discrimination, we fight for drug policies that prioritize people who use drugs, we empower women who use drugs. We believe that every life matter, and we are satisfied with small changes every day. That way, we believe that with time, we will contribute significantly to changing lives for the better.